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Marginal Zone Lymphomas

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Marginal zone lymphomas (MZL) are indolent B-cell lymphomas. When marginal zone lymphomas involve the lymph nodes they are called nodal marginal zone B-cell lymphomas whereas when they involve places outside the lymph nodes (gastrointestinal tract, thyroid, breast, or skin) they are called mucosa-associated lymphatic tissue lymphomas (MALT or MALToma). Splenic (in the spleen) Marginal zone lymphomas  are considered a third separate type. Together they represent less than 20% of all lymphomas.
 
Under the new WHO Lymphoma Classification System (2001), all three types of Marginal Zone Lymphoma are considered distinct entities and may be treated and studied separately.
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Further Reading / In-Depth

Non-Hodgkin's Lymphomas, Peter M. Mauch (Editor), James O. Armitage (Editor), et al., 2004.

  • Section IV: Pathology, Biology, Clinical Evaluation, and Treatment Section
    • Chapter 22: Extranodal Marginal Zone B-Cell Lymphoma of Mucosa-Associated Lymphoid Tissue
    • Chapter 23: Nodal Marginal Zone B-Cell Lymphoma

Excellent but Technical: An Illustrated Guide to Skin Lymphomas, Cerroni, Gatter, Kerl, 2nd. Ed, 2005

  • Chapter 10: Marginal Zone Lymphoma and Cutaneous Immunocytoma

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Non-Hodgkin's Lymphoma Information Pages:

    Non-Hodgkin's Lymphomas
    Non-Hodgkin's Lymphoma: Diagnosis
    Non-Hodgkin's Lymphoma: Aggressive Lymphomas
    Non-Hodgkin's Lymphoma: Indolent Lymphomas
    Non-Hodgkin's Lymphoma: Treatment
    Non-Hodgkin's Lymphoma: Resources
    Bone Marrow and Stem Cell Transplants

Other Pages of Interest:


This page is a work in progress - if you have more complete information, references, or other information please contact the author. The author is not in the medical field and does not warrant the correctness of the material on this page or the sites linked - please take online information and consult with your own medical team to make informed decisions.

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Updated October 30, 2005